Everything You Need to Know About Taking Creatine

Creatine stands out as one of the most well-researched, safe, and effective supplements available today. Trusted by the sports community for decades, its latest scientific breakthroughs reveal benefits that extend far beyond athletics, encompassing cognitive health, aging, women’s wellness, and rehabilitation.

At Jenerise, we help you harness creatine’s full potential as a functional ingredient, enabling your products to meet the growing demand for science-backed wellness supplements that your consumers want.

What is Creatine?

Creatine is a naturally occurring compound produced by the body through a multistage process in the kidneys, pancreas, and liver from the amino acids arginine, glycine, and methionine. Though made from amino acids, creatine itself is not an amino acid.

It’s found naturally in animal-based foods like meat, poultry, and fish (but not in plants), making creatine supplementation critical for plant-based consumers.

About 95% of creatine is stored in muscles, brain, organs, and other cells, delivered via the bloodstream. Its primary role? Powering cellular energy production to support muscle function, brain health, and overall wellness.

How is Creatine Monohydrate Manufactured?

Creatine monohydrate is synthesized by combining sarcosinate (N-methylglycinate) and cyanamide under heat and pressure in a controlled reactor. This process produces pure creatine crystals, which are carefully purified, dried, and milled into a fine 200-mesh powder to optimize solubility and performance.

Is Creatine Safe?

Creatine is one of the safest, most studied supplements on the market:

• Daily doses of 3-5 grams are safe for healthy adults.

• It poses no harm to the kidneys or liver.

• Creatine is not a steroid, nor does it cause male pattern baldness.

• Over 680 clinical studies confirm its safety for all ages.

Regulatory agencies confirm this:

• FDA (USA): Classified creatine monohydrate as GRAS (Generally Recognized as Safe) for use in foods and beverages since 2020.

• EFSA (EU): Approves creatine for muscle strength and performance improvements.

Creatine’s Growing Demand in Health & Wellness Products

Your consumers want more than performance, they want energy, cognitive support, and overall health.

• Enhanced athletic performance: More strength, power, and quicker recovery.

• Cognitive benefits: Better memory, attention, and mental endurance.

• Cardiovascular support: Increased energy production, improved oxygen efficiency, and hydration during exercise.

• Age-related health: Combats muscle loss and supports brain health.

Creatine in Your Products

Until today, creatine’s stability in liquid or moisture-rich formats has been a challenge due to its natural degradation into creatinine. Jenerise delivers breakthrough technology and innovative solutions that overcome this barrier, enabling creatine to be effectively added into ready-to-drink (RTD), ready-to-mix (RTM), and ready-to-eat (RTE) product formats without compromising efficacy or shelf life.

Who Should Take Creatine?

Creatine supports anyone looking to improve muscle mass, cognitive function, cardiovascular fitness, or overall vitality.

Who might be hesitant to consume it due to the current extent of scientific research?

• Pregnant or breastfeeding women

• Children

How Creatine Works

Creatine regenerates ATP (adenosine triphosphate), your cells’ energy currency, especially during high-intensity activity. Acting like a rapid recharge system, it enables harder training, faster recovery, and peak performance, whether in the gym, the office, or life.

Potential Therapeutic Applications

Emerging research explores creatine’s role in conditions like dementia, Parkinson’s, muscular dystrophy, and rehabilitation, highlighting its promise beyond sports.

Potential Side Effects

• Minor weight gain from water retention is common.

• Some may experience mild stomach discomfort during loading phases.

• Staying well-hydrated is crucial.

The Jenerise Advantage

With over 18,000 scientific publications backing creatine’s benefits, Jenerise helps you access high-quality creatine monohydrate through trusted partners, paired with expert liquid stable formulation support and regulatory guidance to ensure you get the right ingredient, in the right format, to meet your customers’ evolving needs and bring your product vision to life.

This positions your brand at the forefront of functional ingredient trends while satisfying consumer demand for transparent, effective products.