Decoding creatine with Dr Blaise Collins
Dr Blaise Collins, PhD, ACSM-EP-C, writes monthly on the science shaping how we understand disease and recovery: creatine's emerging role in Alzheimer's and neurodegeneration, its clinical relevance alongside treatments like semaglutide, and the evidence connecting brain, muscle, and metabolic health.
Dr Blaise’s creatine articles
About Dr Blaise
Dr Patrick Blaise Collins is a Scientific Communicator and Exercise Physiologist with 16 years of experience spanning neurological diseases, cardiovascular and metabolic diseases, and artificial intelligence. Based in San Antonio, TX, he combines academic and research expertise with the real-world "patient voice" and community insights gained from volunteering to bridge the gap between complex science and practical application, to improve the public's access and understanding of those data.
As an entrepreneur, Blaise's oversight of MindForge Communications focuses on telling the story of the data in a way that is both digestible and immediately actionable. Rather than relying on trends or assumptions, he translates complex scientific evidence into clear, actionable insights for audiences ranging from community centres to top-tier academic and clinical key opinion leaders. Whether writing about exercise, pharmaceutical industry interests, or resiliency, Blaise is committed to helping readers understand not just what works, but why it works through the lens of current scientific evidence and ongoing data generation endeavours.
Originally trained in Exercise Physiology, Blaise's career has included guiding projects supporting the launch of the first disease-modifying therapy for Alzheimer's, business development in cardiovascular and musculoskeletal disorders, technical writing for AI applications in radiology, and aiding the growth of blood-based biomarkers as diagnostics in neurological diseases. Every article begins with the same question: "What educational gaps are not being sufficiently addressed by physicians?" That principle informs every recommendation, interpretation of the literature, and educational resource Blaise creates.
Beyond Medical Writing and community education, Blaise is also an avid gardener, powerlifter, and blacksmith. His volunteer work includes the Communications Committee of the San Antonio Mayor's Fitness Council and the Older Adults Resource Group of San Antonio, and he is always looking to connect with the community. He believes that scientific evidence has its greatest value when it can be translated into meaningful improvements or actionable insights, and approaches every project with curiosity, precision, and innovation. His goal is simple: to empower individuals and organisations by telling the story of the data, providing them with the tools and confidence to share that information further.
Frequently asked questions
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Dr Collins traces creatine's decades-long link to brain energy metabolism and examines the CABA trial, in which Alzheimer's patients showed improved working memory, reading recognition, and inhibitory control after 8 weeks of creatine supplementation.
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Dr Collins explains the neurological mechanisms behind creatine's emerging role in mental health, drawing on clinical evidence around brain energy metabolism and its relationship to depression.
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Dr Collins shares his current clinical view on creatine and Parkinson's disease, outlining where mechanistic evidence already exists and where meaningful research opportunities remain.
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Muscle is not just about strength or appearance… it's a metabolic organ deeply linked to long-term health outcomes, independence, and mortality risk. Isabelle explains the functional benchmarks worth knowing and why building and maintaining muscle in your 40s and 50s is one of the highest-leverage things you can do for your future self.
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Dr Collins is clear that creatine should not be framed as an anticancer therapy, but breaks down the growing scientific interest in whether manipulating creatine availability could influence the metabolic hallmarks of cancer as a supportive measure.
Blaise Collins, PhD, ACSM-EP-C traces creatine's decades-long link to brain energy metabolism and unpacks what a groundbreaking new trial reveals about its potential role in Alzheimer's care.